#386 - Cancer Injustice -- Part 1
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چکیده
Cancers are not distributed evenly among the U.S. population. AfricanAmericans, who make up about 12.6% of the population, have more than their fair share of cancer problems, whether we measure incidence rates (occurrence of new cancer cases per 100,000 population) or mortality rates (deaths per 100,000 population) or 5-year survival rates (the proportion of a population that survives for 5 years after diagnosis). Furthermore, as time passes, the cancer situation for African-Americans is deteriorating, relative to whites.
منابع مشابه
Phase 1 study of AMG 386, a selective angiopoietin 1/2-neutralizing peptibody, in combination with chemotherapy in adults with advanced solid tumors.
PURPOSE To evaluate the safety, pharmacokinetics, and antitumor activity of AMG 386, an investigational selective angiopoietin 1/2-neutralizing peptibody, in combination with FOLFOX-4 (F), carboplatin/paclitaxel (C/P), or docetaxel (D), in adult patients with advanced solid tumors. EXPERIMENTAL DESIGN Three cohorts of patients (F, n = 6; C/P, n = 8; D, n = 12) received one full cycle of chemo...
متن کاملPhase II randomized, double-blind, placebo-controlled study of AMG 386 (trebananib) in combination with cisplatin and capecitabine in patients with metastatic gastro-oesophageal cancer.
BACKGROUND We evaluated AMG 386, an investigational peptibody that neutralizes the interaction between angiopoietins-1 and -2 and the Tie2 receptor, combined with cisplatin/capecitabine (CX) as first-line treatment for metastatic gastro-oesophageal cancer. PATIENTS AND METHODS Patients with metastatic gastric, gastro-oesophageal junction, or distal oesophageal adenocarcinoma were randomized 1...
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تاریخ انتشار 2002